Leiomyoma of the epididymis

Michael Platanas, Ioannis Solinis, Eftichios Stavroulakis


Neoplasms of the epididymis are distinguished into benign and malignant, are very rare and are frequently diagnosed as benign neoplasms. Leiomyomas are benign tumors that may arise from any structure or organ containing smooth muscle fibers.


Τα νεοπλάσματα της επιδιδυμίδας διακρίνονται σε καλοήθη και κακοήθη, είναι πολύ σπάνια και μεταξύ αυτών συχνότερα διαγιγνώσκονται τα καλοήθη νεοπλάσματα. Τα λειομυώματα είναι καλοήθη νεοπλάσματα που μπορεί να προκύψουν από οποιαδήποτε δομή ή όργανο περιέχει λείες μυικές ίνες.


Leiomyoma; epididymis; testicle;Λειομύωμα; επιδιδυμίδα; όρχις

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Siegal GP, Gaffey TA: Solitary leiomyomas arising from the tunica dartos scroti. J Urol 1976, 116:69.

Chiong E, Tan KB, Siew E, Rajwanshi A, See H, Esuvaranathan K: Uncommon benign intrascrotal tumours. Ann Acad Med Singapore 2004, 33:351.

Ragsdale BD: Tumours of fatty, muscular and osseous tissue: fat as a tissue, an organ and a source of tumors. In Lever’s Histopathology of the Skin. 8th edition. Edited by Elder D, Elenitsas R, Jaworsky C, Johnson B Jr. Philadelphia, PA: Lippincott - Raven; 1997:457-502.

Holstein AF, Otlandini GE, Baumgarten HG: Morphological analysis of tissue components in the tunica dartos of man. Cell Tissue Res 1974, 154:329.

Das AK, Bolick D, Little NA, Walther PJ: Pedunculated scrotal mass: leiomyoma of scrotum. Urology 1992, 39:376.

Sherwani RK, Rahman K, Akhtar K, Zaheer S, Hassan MJ, Haider A: Leiomyoma of scrotum. Indian J Pathol Microbiol 2008, 51:72.

Belis JA, et al.: Genitourinary leiomyomas. Urology 1979, 13(4):424 - 9.

Borri A, et al.: Bizarre leiomyoma of the epididymis. A case report. Minerva Urol Nefrol 2000, 52(1):29 - 31.

De Rosa G, et al.: Symplastic leiomyoma of the scrotum. A case report. Pathologica 1996, 88(1):55 - 7.

Robboy SJ, et al.: Pathology and pathophysiology of uterine smooth - muscle tumours. Environ Health Perspect 2000, 108(Suppl 5):779 - 84.

Habuchi T, et al.: Leiomyoma of the scrotum: a case report and sonographic findings. Hinyokika Kiyo 1990, 36(8):959 - 62.

Kim NR, et al.: Bizarre leiomyoma of the scrotum. J Korean Med Sci 2003, 18(3):452 - 4.

Cabello Benavente R, et al.: Giant bizarre scrotal leiomyoma. Arch Esp Urol 2004, 57(8):847 - 51.

Sevilla Chica F, et al.: Atypical or bizarre leiomyoma of the scrotum. Report of one case and bibliographic review. Arch Esp Urol 2004, 57(4):428 - 31.

Slone S, et al.: Scrotal leiomyomas with bizarre nuclei: a report of three cases.

Belis JA, Post GJ, Rochman SC, Milan DF. Genitourinary leiomyomas. Urology 1979;13:424.

Chiaramonte RM. Leiomyoma of tunica albuginea of testis. Urology 1988;31:344 - 5.

Albert PS, Mininberg DT. Leiomyoma of tunica albuginea. J Urol 1972;107:869 - 71.

Honore LH, Sullivan LD. Intratesticular leiomyoma: a case report with discussion of differential diagnosis and histogenesis. J Urol 1975;114:631 - 5.

Bitker MO, Leo JP, Jardin A, Chatelain Ch. Les tumours rares du testicule. A propos de quinze observations. Ann Urol 1986;20:238 - 243. [in French].

Nino-Murcia M, Kosek J. Leiomyoma of the testis: sonographic and pathologic findings. J Can Assoc Radiol1989;40:178 - 9.

Takahashi G, Takahashi H. Intratesticular leiomyoma: a case report. Acta Urol Jpn 1991;37:1551 - 3.

Thomas J, Rifkin M, Nazeer T. Intratesticular leiomyoma of the body of the testis. J Ultrasound Med 1998;17:785 - 7.

Destito A, Servello C, Pisanti F, Pierconti F, Candidi MO, Lacquaniti S. Leiomyoma of the testis. Scand JUrol Nephrol 1999;33:338 - 9.

Remzi D. Tumors of the tunica vaginalis. South Med J1973;66:841 - 2.

Lia - Beng T, Wei - Wuang H, Biing - Rorn C, Chia - Chun T. Bilateral synchronous leiomyomas of the testicular tunica albuginea. A case report and review of the literature. Int Urol Nephrol 1996;28:549 - 552.

Richie JP, Steele GS. Neoplasms of the testis, Chapt.81, In: Kavoussi LR, Novick AC, Partin AW, Peters CA, eds. Campbell’s urology, 8th ed., Philadelphia, PA: Elsevier Science, 2003;2876 - 919.

Maria NS, Emilia R: Leiomyoma of the tunica albuginea. Urologia 1979; 46: 768.

Aus G, Boiesen PT. Bilateral leiomyoma of the tunica albuginea. Scand J Urol Nephrol 1991;25:79 - 80.

Heidenreich A, Moul JW, Srivastava S, Engelmann UH. Synchronous bilateral testicular tumour nonseminomatous germ cell tumours and contralateral benign tumours. Scand J Urol Nephrol 1997;31:389 - 92.

Longchampt E, Carriou G, Arborio M, Skrobala E,Brouland J, Cochand-Priollet B. Le leiomyome intratesticulaire: une localisation exceptionnelle. Ann Pathol 1998;18:418 - 21. [In French].

Gonzalez CM, Victor TA, Bourtsos E, Blum MD. Monoclonal antibody confirmation of a primary leiomyoma of the testis. J Urol 1999;161:1908.

Mak CW, Tzeng WS, Chou CK, Chen CY, Chang JM,Tzeng CC. Leiomyoma arising from the tunica albuginea of the testis: sonographic findings. J Clin Ultrasound 2004;32:309 - 11.

Chiong E, Tan KB, Siew E, Rajwanshi A, Esuvaranathan K. Uncommon benign intrascrotal tumors . Ann Acad Med Singapore 2004; 33:351 - 5.

Beccia D J, Krane R J, Olsson C A. Clinical management of nontesticular intrascrotal tumors. J Urol 1976; 116: 476.

Tammela T L J, Karttunen T J, Makarainen H P et al. Intrascrotal adenomatoid tumors. J Urol 1991; 146: 61.

Nistal M, Contreras F, Paniagua R. Adenomatoid tumour of the epididymis: Histochemical and ultrastructural study of 2 cases. Br J Urol 1978; 50: 121.

Delahunt B, King J N, Bethwaite P B et al. Immuno - histochemical evidence for mesothelial origin of para - testicular adenomatoid tumour. Histopathology 2000; 36: 109 -115.

Lee J C, Bhatt S, Dogra V S, Imaging of the Epididymis Ultrasound Quarterly March 2008; Volume 24 (1).

Akbar S A, Sayyed T A, Neil J S A: Multimodality Imaging of Para testicular Neoplasms and their rare mimics Radiographics Nov 2003.

Woodward P J, Schwab C M, Sesterhenn I A, From the Archives of AFIP: extratesticular scrotal masses: radiologic-pathologic correlation. Radiographics 2003; 23:215 - 240.

Klerk D P, Nime F. Adenomatoid tumor (mesothelioma) of testicular and paratesticular tissue. Urology 1975; 6: 635 (s).

Manson A L. Adenomatoid tumor of the testicular tunica albuginea mimicking testicular carcinoma J Urol 1988; 139: 819 - 820 (s).

Mazella F M, Sieber S C, Lopez V. Histiocytous Hemangioma of the testis. J Urol 1995; 153: 743 - 744 (s).

Shveta G, Mathew M. Adenomatoid Tumor of Tunica Albuginea Mimicking a Testicular Neoplasm. The Internet Journal of Urology 2007; 4 (2).

DOI: http://dx.doi.org/10.19264/hj.v27i2.83