Green therapies for a grey disease

Konstantinos Stamatiou


Phytotherapeutic agents are used for many years as an adjunctive therapy of benign prostatic hypertrophy. The similarity of the symptoms of the lower urinary tract associated with chronic prostatitis with those caused by benign prostatic hypertrophy and the anecdotally observed efficacy of the phytotherapeutic agents in the improvement of pelvic pain justifies their use in the treatment of chronic nonbacterial prostatitis. Many clinicians and researchers have investigated the role of herbal medicinal products against the symptoms of the lower urinary tract however a careful review of the reported studies showed that specific studies for nonbacterial prostatitis are limited. Even if in these studies the target, the material and the methods varies, most support their usefulness. Despite the general belief that phytotherapeutic agents’ have a dual mechanism of action (both hormonal and anti-inflammatory) it seems that they actually exhibit a moderate anti-inflammatory effect the exact mechanism of which is not fully investigated.


Τα φυτοθεραπευτικά χρησιμοποιούνται εδώ και πολλά χρόνια ως συμπληρωματική θεραπεία στην καλοήθη υπερτροφία του προστάτη. Η ομοιότητα των συμπτωμάτων του κατώτερου ουροποιητικού στη χρόνια προστατίτιδα με αυτά που προκαλούνται από την καλοήθη υπερτροφία του προστάτη και η παρατηρούμενη αποτελεσματικότητα των φυτοθεραπευτικών στη βελτίωση του πυελικού πόνου δικαιολογεί τη χρήση τους στη θεραπεία της χρόνιας μη βακτηριακής προστατίτιδας. Πολλοί κλινικοί γιατροί και ερευνητές έχουν διερευνήσει το ρόλο των φυτικών φαρμακευτικών προϊόντων κατά των συμπτωμάτων του κατώτερου ουροποιητικού συστήματος, ωστόσο μια προσεκτική εξέταση των υφιστάμενων μελετών έδειξαν ότι οι εξειδικευμένες για τη μη βακτηριακή προστατίτιδα είναι περιορισμένες. Ακόμα και αν σε αυτές τις μελέτες ο στόχος, το υλικό και οι μέθοδοι ποικίλλουν οι περισσότερες υποστηρίζουν τη χρησιμότητά τους. Παρά τη γενική πεποίθηση ότι τα φυτοθεραπευτικά, έχουν διπλό μηχανισμό δράσης (ορμονικό και αντί-φλεγμονώδη) φαίνεται ότι εμφανίζουν μία μέτρια αντιφλεγμονώδη δράση της οποίας ο ακριβής μηχανισμός δεν έχει πλήρως διερευνηθεί.


chronic nonbacterial prostatitis; chronic pelvic pain syndrome; lower urinary tract symptoms; pharmacotherapy; phytotherapeutic drugs; xρόνια μη βακτηριακή προστατίτιδα; σύνδρομο χρόνιου πυελικού άλγους; συμπτώματα από το κατώτερο ουροποιητικό σύστημα;

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